{"id":8651,"date":"2024-04-22T09:13:17","date_gmt":"2024-04-22T01:13:17","guid":{"rendered":"https:\/\/www.1ai.net\/?p=8651"},"modified":"2024-04-22T09:13:17","modified_gmt":"2024-04-22T01:13:17","slug":"ai-%e5%b0%86%e5%b8%95%e9%87%91%e6%a3%ae%e7%97%85%e8%8d%af%e7%89%a9%e8%ae%be%e8%ae%a1%e6%8f%90%e9%80%9f%e5%8d%81%e5%80%8d%ef%bc%8c%e5%8f%af%e8%af%86%e5%88%ab%e9%98%bb%e6%ad%a2%e8%af%a5%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.1ai.net\/en\/8651.html","title":{"rendered":"AI accelerates Parkinson&#039;s disease drug design tenfold, identifying small molecules that prevent protein aggregation characteristic of the disease"},"content":{"rendered":"<p data-vmark=\"b0d8\">According to the official website of the University of Cambridge in the UK, researchers at the university have greatly accelerated<a href=\"https:\/\/www.1ai.net\/en\/tag\/%e5%b8%95%e9%87%91%e6%a3%ae\" title=\"[Sees articles with [Pakinson] labels]\" target=\"_blank\" >Parkinson&#039;s<\/a>The development of disease treatments.<\/p>\n<p data-vmark=\"a2e8\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-8652\" title=\"3a44d115-04c9-40b0-9dfe-799b501bfe08\" src=\"https:\/\/www.1ai.net\/wp-content\/uploads\/2024\/04\/3a44d115-04c9-40b0-9dfe-799b501bfe08.png\" alt=\"3a44d115-04c9-40b0-9dfe-799b501bfe08\" width=\"927\" height=\"1057\" \/><\/p>\n<p data-vmark=\"3fbb\">The researchers designed and used a <a href=\"https:\/\/www.1ai.net\/en\/tag\/ai\" title=\"[View articles tagged with [AI]]\" target=\"_blank\" >AI<\/a> strategy,<span class=\"accentTextColor\">To identify and block alpha-synuclein<\/span>(IT Home Note: Characteristic protein of Parkinson&#039;s disease)<span class=\"accentTextColor\">Aggregated small molecules<\/span>This is also one avenue for finding potential treatments for Parkinson&#039;s disease.<\/p>\n<p data-vmark=\"2e6a\">The Team<span class=\"accentTextColor\">Using machine learning techniques, a chemical library containing millions of entries was quickly screened<\/span>, to identify small molecules that bind to amyloid aggregates and prevent their proliferation, ultimately identifying five highly effective compounds for further study.<\/p>\n<p data-vmark=\"b8b7\">Leveraging artificial intelligence,<span class=\"accentTextColor\">The initial screening process is now 10 times faster and costs 1\/1000th of what it was before<\/span>, making the development of potential Parkinson&#039;s disease treatments significantly faster than before. According to Professor Michelle Vendroscolo, the leader of the study,<span class=\"accentTextColor\">Machine learning is having an impact on the drug discovery process, speeding up the process of identifying the most promising drug candidates.<\/span>Due to the significant reduction in time and cost, multiple drug development programs can be implemented in the future.<\/p>\n<p data-vmark=\"42eb\">The research results have been published in the journal Nature Chemical Biology.<a href=\"https:\/\/www.nature.com\/articles\/s41589-024-01580-x\" target=\"_blank\" rel=\"noopener\">Click here to go<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>According to the official website of the University of Cambridge in the UK, researchers at the university have dramatically accelerated the process of developing treatments for Parkinson's disease through artificial intelligence technology. The researchers designed and used an AI-based strategy so as to identify small molecules that prevent the aggregation of \u03b1-synuclein (IT House note: the characteristic protein of Parkinson's disease). This is also a way to find potential treatments for Parkinson's disease. Using machine learning techniques, the team quickly screened a chemical library of millions of entries to identify small molecules that bind to amyloid aggregates and prevent their proliferation, ultimately identifying five highly effective compounds for further study. With the \"power\" of artificial intelligence, the initial screening process has now been sped up 10-fold and reduced to one-thousandth of the original cost, enabling the development of a Parkinson's disease<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[146],"tags":[411,2329,2330],"collection":[],"class_list":["post-8651","post","type-post","status-publish","format-standard","hentry","category-news","tag-ai","tag-2329","tag-2330"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/posts\/8651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/comments?post=8651"}],"version-history":[{"count":0,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/posts\/8651\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/media?parent=8651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/categories?post=8651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/tags?post=8651"},{"taxonomy":"collection","embeddable":true,"href":"https:\/\/www.1ai.net\/en\/wp-json\/wp\/v2\/collection?post=8651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}